Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on quality, location and traveller experience. Last updated on .
Hotels in Cape Girardeau
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3 Sept - 4 SeptTomorrow
4 Sept - 5 SeptThis weekend
4 Sept - 6 SeptNext weekend
11 Sept - 13 SeptWhere to stay in Cape Girardeau?
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
Rp2.222.151
Rp2.518.008 total
includes taxes & fees
13 Sept - 14 Sept
The Riverview
The RiverviewCape Girardeau
Rp2.020.710
Rp2.279.530 total
includes taxes & fees
8 Sept - 9 Sept
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
Rp1.767.723
Rp1.994.239 total
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
Rp1.794.063
Rp2.041.894 total
includes taxes & fees
6 Sept - 7 Sept
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
Rp1.272.711
Rp1.435.797 total
includes taxes & fees
4 Oct - 5 Oct
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
Rp1.590.933
Rp1.794.796 total
includes taxes & fees
13 Sept - 14 Sept
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
Rp1.788.231
Rp2.017.375 total
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
Rp1.870.085
Rp2.109.718 total
includes taxes & fees
4 Oct - 5 Oct
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
Rp1.587.657
Rp1.806.976 total
includes taxes & fees
20 Sept - 21 Sept
Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
Rp1.086.021
Rp1.225.183 total
includes taxes & fees
4 Oct - 5 Oct
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
Rp1.449.678
Rp1.732.675 total
includes taxes & fees
4 Oct - 5 Oct
Town House Inn Cape Giradreau
Town House Inn Cape GiradreauCape Girardeau
Rp1.325.925
Rp1.549.034 total
includes taxes & fees
4 Oct - 5 Oct
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
Rp1.420.862
Rp1.502.207 total
includes taxes & fees
7 Sept - 8 Sept
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
Rp1.406.541
Rp1.522.230 total
includes taxes & fees
4 Oct - 5 Oct
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
Rp1.493.335
Rp1.625.492 total
includes taxes & fees
6 Sept - 7 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
Rp1.637.959
Rp1.772.681 total
includes taxes & fees
4 Oct - 5 Oct
Hotel 7 Inn Anna
Hotel 7 Inn AnnaAnna
Rp1.558.703
Rp1.807.918 total
includes taxes & fees
6 Sept - 7 Sept
Makanda Inn
Makanda InnMakanda
Rp4.652.770
Rp5.304.158 total
includes taxes & fees
6 Sept - 7 Sept
Town House Inn
Town House InnJackson
Rp1.266.147
Rp1.370.288 total
includes taxes & fees
6 Sept - 7 Sept
Check out pet-friendly hotels in Cape Girardeau
Rp1.272.711
Rp1.435.797 total
includes taxes & fees
4 Oct - 5 Oct
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
Rp1.767.723
Rp1.994.239 total
includes taxes & fees
13 Sept - 14 Sept
Rp1.590.933
Rp1.794.796 total
includes taxes & fees
13 Sept - 14 Sept
Rp1.587.657
Rp1.806.976 total
includes taxes & fees
20 Sept - 21 Sept
Rp1.870.085
Rp2.109.718 total
includes taxes & fees
4 Oct - 5 Oct
Rp1.449.678
Rp1.732.675 total
includes taxes & fees
4 Oct - 5 Oct
Rp1.325.925
Rp1.549.034 total
includes taxes & fees
4 Oct - 5 Oct
You may also like hotels with pools in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
Rp1.767.723
Rp1.994.239 total
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
Rp1.794.063
Rp2.041.894 total
includes taxes & fees
6 Sept - 7 Sept
Rp1.590.933
Rp1.794.796 total
includes taxes & fees
13 Sept - 14 Sept
Rp1.587.657
Rp1.806.976 total
includes taxes & fees
20 Sept - 21 Sept
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
Rp1.788.231
Rp2.017.375 total
includes taxes & fees
4 Oct - 5 Oct
Rp1.870.085
Rp2.109.718 total
includes taxes & fees
4 Oct - 5 Oct
Rp1.086.021
Rp1.225.183 total
includes taxes & fees
4 Oct - 5 Oct
Rp1.449.678
Rp1.732.675 total
includes taxes & fees
4 Oct - 5 Oct
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Cape Girardeau
Pet friendly
Family friendly
Our prices for hotels in Cape Girardeau are cheapest in June
Our prices for hotels in Cape Girardeau are cheapest in June
Price trends for hotels in Cape Girardeau
Pricing is based on two traveller single night rates
Top landmarks in Cape Girardeau
Southeast Missouri State University
8.8/10 (248 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
Riverfront Bridge Park
8.8/10 (129 reviews)
Riverfront Bridge Park is worth a visit, located 0.7 mi (1.1 km) from central Cape Girardeau.
Century Casino & Hotel Cape Girardeau
8.4/10 (176 reviews)
Century Casino & Hotel Cape Girardeau is 0.5 mi (0.8 km) from central Cape Girardeau, why not stop by during your stay?
Hunter Valley Winery
7.4/10 (48 reviews)
Travellers might want a tour of Hunter Valley Winery, just one of the places to visit, located 9.3 mi (14.9 km) from central Cape Girardeau.
Riverfront Park
8.0/10 (2 reviews)
Riverfront Park is worth a visit when in central Cape Girardeau.
Show Me Center
8.6/10 (40 reviews)
You can catch an event at Show Me Center, located 1.1 mi (1.8 km) from central Cape Girardeau.
Cape Rock Park
8.6/10 (36 reviews)
Cape Rock Park is worth a visit, located 1.9 mi (3.1 km) from central Cape Girardeau.
Cape Splash Family Aquatic Center
8.6/10 (21 reviews)
Why not give yourself a treat with a trip to Cape Splash Family Aquatic Center, one of the family attractions located 3.1 mi (5.1 km) from central Cape Girardeau? If you have fun at Cape Splash Family Aquatic Center, you'll love Cape Girardeau Conservation Nature Center, located nearby.
Learn more about Cape Girardeau
Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.
See all hotels in Cape Girardeau
Check out reviews of Cape Girardeau hotels guests love
Pear Tree Inn Cape Girardeau West
10/10 Excellent
"Clean room friendly staff"
Tru By Hilton Cape Girardeau
10/10 Excellent
"Clean, quiet - and EV chargers both on and adjacent (Tesla Supercharger) to hotel property."
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
10/10 Excellent
"This location is a must stay any time I am traveling in the area. The staff are helpful. There are lots of dinning options near by. I can always count on a peaceful night sleep at this location."
Candlewood Suites Cape Girardeau by IHG
10/10 Excellent
"Beautiful nice clean place. Beds are so comfortable too! Just wished they offered breakfast"
Fairfield Inn & Suites by Marriott Cape Girardeau
10/10 Excellent
"The room was beautiful and had everything needed!! So clean!"
Town House Inn Cape Giradreau
10/10 Excellent
"If your looking for a budget friendly hotel to stay that is clean or if you need a place to call home for a month till you find a place, I highly recommend this hotel."
Frequently asked questions
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