Hotels in Old Appleton

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Top 5 hotels in Old Appleton at a glance

1. The Riverview — 4-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
2. Drury Plaza Hotel Cape Girardeau Conference Center — 3-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.
3. Drury Inn & Suites Cape Girardeau — 3-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau — 3-star hotel in Jackson. Guest rating: 9.0/10 — Wonderful.
5. Pear Tree Inn Cape Girardeau West — 2.5-star hotel in Cape Girardeau. Guest rating: 9.2/10 — Wonderful.

Where to stay in Old Appleton?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Old Appleton on Hotels.com. These Old Appleton hotels consistently deliver on quality, location and traveler experience. Last updated on September 19, 2026.

Grand Riverview Two Queen Room | Premium bedding, pillowtop beds, in-room safe, desk

Jackpot Suite | Living area | LED TV, Netflix, Hulu, first-run movies

1. The Riverview

Cape Girardeau

$107 nightly

$120 total

Sep 21 - Sep 22

Total with taxes and fees

2. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

$100 nightly

$113 total

Sep 24 - Sep 25

Total with taxes and fees

Desk, laptop workspace, blackout drapes, iron/ironing board

3. Drury Inn & Suites Cape Girardeau

Cape Girardeau

$90 nightly

$102 total

Sep 24 - Sep 25

Total with taxes and fees

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

$84 nightly

$91 total

Sep 20 - Sep 21

Total with taxes and fees

Desk, laptop workspace, blackout drapes, cribs (free)

5. Pear Tree Inn Cape Girardeau West

Cape Girardeau

$72 nightly

$81 total

Sep 27 - Sep 28

Total with taxes and fees

6. Drury Inn & Suites Jackson MO

Jackson

$85 nightly

$90 total

Sep 24 - Sep 25

Total with taxes and fees

Suite, 1 King Bed | Premium bedding, down comforters, pillowtop beds, in-room safe

Indoor pool, open 8 AM to 11 PM, sun loungers

7. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

$101 nightly

$115 total

Sep 27 - Sep 28

Total with taxes and fees

In-room safe, desk, iron/ironing board, WiFi (free)

8. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

$112 nightly

$124 total

Sep 29 - Sep 30

Total with taxes and fees

9. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

$125 nightly

$142 total

Oct 2 - Oct 3

Total with taxes and fees

10. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

$88 nightly

$105 total

Oct 4 - Oct 5

Total with taxes and fees

11. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

$101 nightly

$114 total

Sep 24 - Sep 25

Total with taxes and fees

12. Tru By Hilton Cape Girardeau

Cape Girardeau

$89 nightly

$102 total

Oct 4 - Oct 5

Total with taxes and fees

In-room safe, desk, blackout drapes, soundproofing

13. Holiday Inn Express & Suites Perryville by IHG

Perryville

$101 nightly

$116 total

Sep 27 - Sep 28

Total with taxes and fees

Egyptian cotton sheets, premium bedding, down comforters

14. Quality Inn Cape Girardeau North

Cape Girardeau

$59 nightly

$67 total

Sep 27 - Sep 28

Total with taxes and fees

15. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

$106 nightly

$119 total

Sep 27 - Sep 28

Total with taxes and fees

16. EC Reed's Mercantile and Hotel

Marble Hill

$92 nightly

$100 total

Sep 20 - Sep 21

Total with taxes and fees

Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes

17. Super 8 by Wyndham Perryville

Perryville

$71 nightly

$82 total

Oct 4 - Oct 5

Total with taxes and fees

Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Deluxe Studio Suite, 1 King Bed, Non Smoking | Bathroom | Hair dryer, towels

18. Baymont by Wyndham Chester IL

Chester

$94 nightly

$104 total

Sep 22 - Sep 23

Total with taxes and fees

19. The Atrium - A Boutique Hotel

Perryville

$158 nightly

$181 total

Sep 20 - Sep 21

Total with taxes and fees

Coffee/tea maker, full-size fridge, microwave, oven

Urban Loft 1 | Egyptian cotton sheets, premium bedding, down comforters

55-inch Smart TV with digital channels, TV, streaming services

20. Urban Lofts

Perryville

$295 nightly

$338 total

Sep 20 - Sep 21

Total with taxes and fees

View all properties

Go beyond your typical stay in Old Appleton

Pet friendly

Pool

Check out reviews of Old Appleton hotels guests love

Tru By Hilton Cape Girardeau

10/10 Excellent

"The staff is always super kind and helpful"

Super 8 by Wyndham Perryville

8/10 Good

"Average selection of breakfast items."

Quality Inn Cape Girardeau North

8/10 Good

"No complaints"

Holiday Inn Express & Suites Perryville by IHG

8/10 Good

"Clean and nice. Late check in but staff was very helpful and quick. Bedding was nice, mattress was more firm than I like but not uncomfortable."

Urban Lofts

10/10 Excellent

"Beautiful, clean property in the heart of city center. Many options for food and shopping within short walking distance."

Frequently asked questions

How much does a hotel room cost in Old Appleton?

You can find top hotels in Old Appleton from $67 with options to suit your budget and needs. If you're after an affordable hotel in Old Appleton that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Old Appleton hotels?

Discover great deals on Old Appleton hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Old Appleton hotels.

Can I book Old Appleton hotels with free cancellation?

To book a refundable Old Appleton hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Can I book a refundable hotel in Old Appleton?

If you're looking for the flexibility to change your travel plans to Old Appleton, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Old Appleton be like during my visit?

The warmest months in Old Appleton are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 40°F. The rainiest months are April and March.

Why should I book my Old Appleton hotel through Hotels.com?

There are plenty of reasons to book your Old Appleton travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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